{"id":10283,"date":"2025-04-01T00:29:19","date_gmt":"2025-03-31T16:29:19","guid":{"rendered":"https:\/\/www.51dea.com\/archives\/10283"},"modified":"2025-04-01T00:29:19","modified_gmt":"2025-03-31T16:29:19","slug":"1-%e7%94%b2%e5%9f%ba%e5%92%aa%e5%94%91%ef%bc%88lupragen-nmi%ef%bc%89%e7%9a%84%e4%be%9b%e5%ba%94%e5%95%86%e8%af%84%e4%bc%b0%ef%bc%9a%e9%80%89%e6%8b%a9%e4%bc%98%e8%b4%a8%e5%90%88%e4%bd%9c%e4%bc%99","status":"publish","type":"post","link":"https:\/\/www.51dea.com\/archives\/10283","title":{"rendered":"1-\u7532\u57fa\u54aa\u5511\uff08Lupragen NMI\uff09\u7684\u4f9b\u5e94\u5546\u8bc4\u4f30\uff1a\u9009\u62e9\u4f18\u8d28\u5408\u4f5c\u4f19\u4f34"},"content":{"rendered":"<h1>1-\u7532\u57fa\u54aa\u5511\uff08Lupragen NMI\uff09\u4f9b\u5e94\u5546\u8bc4\u4f30\uff1a\u9009\u62e9\u4f18\u8d28\u5408\u4f5c\u4f19\u4f34\u7684\u5168\u9762\u6307\u5357<\/h1>\n<p>\u5728\u5316\u5b66\u5de5\u4e1a\u8fd9\u7247\u6d69\u701a\u7684\u6d77\u6d0b\u4e2d\uff0c1-\u7532\u57fa\u54aa\u5511\uff08Lupragen NMI\uff09\u72b9\u5982\u4e00\u9897\u7480\u74a8\u7684\u660e\u73e0\uff0c\u4ee5\u5176\u72ec\u7279\u7684\u6027\u80fd\u548c\u5e7f\u6cdb\u7684\u5e94\u7528\u9886\u57df\u5438\u5f15\u4e86\u65e0\u6570\u79d1\u7814\u5de5\u4f5c\u8005\u7684\u76ee\u5149\u3002\u4f5c\u4e3a\u6709\u673a\u5408\u6210\u4e2d\u7684\u91cd\u8981\u4e2d\u95f4\u4f53\uff0c\u5b83\u4e0d\u4ec5\u5728\u533b\u836f\u3001\u519c\u836f\u9886\u57df\u5927\u663e\u8eab\u624b\uff0c\u8fd8\u5728\u6d82\u6599\u3001\u5851\u6599\u6539\u6027\u7b49\u5de5\u4e1a\u5e94\u7528\u4e2d\u626e\u6f14\u7740\u4e0d\u53ef\u6216\u7f3a\u7684\u89d2\u8272\u3002\u7136\u800c\uff0c\u5c31\u50cf\u9009\u8d2d\u4e00\u9897\u5b8c\u7f8e\u7684\u94bb\u77f3\u9700\u8981\u6167\u773c\u8bc6\u73e0\u4e00\u6837\uff0c\u9009\u62e9\u4e00\u5bb6\u4f18\u8d28\u76841-\u7532\u57fa\u54aa\u5511\u4f9b\u5e94\u5546\u4e5f\u9700\u8981\u6211\u4eec\u64e6\u4eae\u53cc\u773c\uff0c\u6df1\u5165\u8003\u5bdf\u3002<\/p>\n<p>\u672c\u6587\u5c06\u5e26\u9886\u8bfb\u8005\u8e0f\u4e0a\u4e00\u573a\u522b\u5f00\u751f\u9762\u7684\u4f9b\u5e94\u5546\u8bc4\u4f30\u4e4b\u65c5\u3002\u6211\u4eec\u5c06\u4ece\u4ea7\u54c1\u53c2\u6570\u3001\u8d28\u91cf\u63a7\u5236\u4f53\u7cfb\u3001\u4f9b\u5e94\u94fe\u7a33\u5b9a\u6027\u7b49\u591a\u4e2a\u7ef4\u5ea6\u8fdb\u884c\u5168\u9762\u5256\u6790\uff0c\u5e76\u901a\u8fc7\u751f\u52a8\u6709\u8da3\u7684\u6bd4\u55bb\u548c\u8be6\u5b9e\u7684\u6570\u636e\u5e2e\u52a9\u60a8\u5feb\u901f\u9501\u5b9a\u7406\u60f3\u7684\u5408\u4f5c\u4f19\u4f34\u3002\u65e0\u8bba\u662f\u5bf9\u4ea7\u54c1\u8d28\u91cf\u6709\u6781\u81f4\u8ffd\u6c42\u7684\u79d1\u7814\u4eba\u5458\uff0c\u8fd8\u662f\u5bf9\u6210\u672c\u6548\u76ca\u654f\u611f\u7684\u751f\u4ea7\u7ecf\u7406\uff0c\u90fd\u80fd\u5728\u8fd9\u7bc7\u6587\u7ae0\u4e2d\u627e\u5230\u81ea\u5df1\u5173\u5fc3\u7684\u7b54\u6848\u3002<\/p>\n<p>\u4e3a\u4e86\u8ba9\u5185\u5bb9\u66f4\u52a0\u76f4\u89c2\u6613\u61c2\uff0c\u6211\u4eec\u5c06\u91c7\u7528\u8868\u683c\u5f62\u5f0f\u5c55\u793a\u5173\u952e\u6570\u636e\uff0c\u5e76\u5f15\u7528\u56fd\u5185\u5916\u6743\u5a01\u6587\u732e\u652f\u6301\u89c2\u70b9\u3002\u540c\u65f6\uff0c\u6211\u4eec\u8fd8\u5c06\u7ed3\u5408\u5b9e\u9645\u6848\u4f8b\uff0c\u4e3a\u60a8\u63ed\u793a\u5982\u4f55\u5728\u7eb7\u7e41\u590d\u6742\u7684\u5e02\u573a\u4e2d\u7b5b\u9009\u51fa\u503c\u5f97\u4fe1\u8d56\u7684\u4f9b\u5e94\u5546\u3002\u8ba9\u6211\u4eec\u4e00\u8d77\u63a2\u7d22\u8fd9\u4e2a\u5145\u6ee1\u6311\u6218\u4e0e\u673a\u9047\u7684\u9886\u57df\u5427\uff01<\/p>\n<hr \/>\n<h2>\u7ae0\uff1a\u8ba4\u8bc61-\u7532\u57fa\u54aa\u5511\uff08Lupragen NMI\uff09<\/h2>\n<h3>1.1 \u4ec0\u4e48\u662f1-\u7532\u57fa\u54aa\u5511\uff1f<\/h3>\n<p>1-\u7532\u57fa\u54aa\u5511\uff0c\u5316\u5b66\u540d\u79f0\u4e3a1-Methylimidazole\uff0c\u7b80\u79f0NMI\uff0c\u662f\u4e00\u79cd\u5177\u6709\u82b3\u9999\u6742\u73af\u7ed3\u6784\u7684\u5c0f\u5206\u5b50\u5316\u5408\u7269\u3002\u5b83\u7684\u5206\u5b50\u5f0f\u4e3aC4H6N2\uff0c\u5206\u5b50\u91cf\u4ec5\u4e3a86.10 g\/mol\u3002\u8fd9\u79cd\u5316\u5408\u7269\u56e0\u5176\u72ec\u7279\u7684\u5316\u5b66\u6027\u8d28\u800c\u5907\u53d7\u9752\u7750\u2014\u2014\u5b83\u65e2\u53ef\u4f5c\u4e3a\u8d28\u5b50\u4f9b\u4f53\uff0c\u53c8\u53ef\u4f5c\u4e3a\u4eb2\u6838\u8bd5\u5242\u53c2\u4e0e\u591a\u79cd\u53cd\u5e94\u7c7b\u578b\uff0c\u5982\u52a0\u6210\u53cd\u5e94\u3001\u53d6\u4ee3\u53cd\u5e94\u4ee5\u53ca\u805a\u5408\u53cd\u5e94\u7b49\u3002<\/p>\n<p>\u4ece\u5916\u89c2\u4e0a\u770b\uff0c1-\u7532\u57fa\u54aa\u5511\u662f\u4e00\u79cd\u65e0\u8272\u81f3\u6d45\u9ec4\u8272\u6db2\u4f53\uff0c\u7565\u5e26\u6c28\u5473\u3002\u5176\u5bc6\u5ea6\u7ea6\u4e3a1.01 g\/cm\u00b3\uff0c\u5728\u5e38\u6e29\u4e0b\u6cb8\u70b9\u4e3a197\u00b0C\uff0c\u7194\u70b9\u5219\u4f4e\u81f3-5\u00b0C\u3002\u8fd9\u4e9b\u7269\u7406\u7279\u6027\u4f7f\u5176\u6613\u4e8e\u50a8\u5b58\u548c\u8fd0\u8f93\uff0c\u540c\u65f6\u4e5f\u4e3a\u5de5\u4e1a\u5e94\u7528\u63d0\u4f9b\u4e86\u6781\u5927\u7684\u4fbf\u5229\u3002<\/p>\n<table>\n<thead>\n<tr>\n<th><strong>\u53c2\u6570<\/strong><\/th>\n<th><strong>\u6570\u503c<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u5206\u5b50\u5f0f<\/td>\n<td>C4H6N2<\/td>\n<\/tr>\n<tr>\n<td>\u5206\u5b50\u91cf<\/td>\n<td>86.10 g\/mol<\/td>\n<\/tr>\n<tr>\n<td>\u5bc6\u5ea6<\/td>\n<td>1.01 g\/cm\u00b3<\/td>\n<\/tr>\n<tr>\n<td>\u6cb8\u70b9<\/td>\n<td>197\u00b0C<\/td>\n<\/tr>\n<tr>\n<td>\u7194\u70b9<\/td>\n<td>-5\u00b0C<\/td>\n<\/tr>\n<tr>\n<td>\u5916\u89c2<\/td>\n<td>\u65e0\u8272\u81f3\u6d45\u9ec4\u8272\u6db2\u4f53<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>1.2 \u5e94\u7528\u9886\u57df<\/h3>\n<p>1-\u7532\u57fa\u54aa\u5511\u7684\u5e94\u7528\u8303\u56f4\u6781\u4e3a\u5e7f\u6cdb\uff0c\u582a\u79f0\u5316\u5b66\u754c\u7684\u201c\u591a\u9762\u624b\u201d\u3002\u4ee5\u4e0b\u662f\u51e0\u4e2a\u4e3b\u8981\u5e94\u7528\u9886\u57df\u7684\u7b80\u8981\u4ecb\u7ecd\uff1a<\/p>\n<h4>1.2.1 \u533b\u836f\u884c\u4e1a<\/h4>\n<p>\u5728\u533b\u836f\u9886\u57df\uff0c1-\u7532\u57fa\u54aa\u5511\u662f\u5236\u5907\u67d0\u4e9b\u6297\u771f\u83cc\u836f\u7269\u548c\u6297\u751f\u7d20\u7684\u5173\u952e\u4e2d\u95f4\u4f53\u3002\u4f8b\u5982\uff0c\u4f0a\u66f2\u5eb7\u5511\uff08Itraconazole\uff09\u7684\u5408\u6210\u8fc7\u7a0b\u4e2d\u5c31\u9700\u8981\u7528\u5230\u8be5\u5316\u5408\u7269\u3002\u6b64\u5916\uff0c\u5b83\u8fd8\u88ab\u7528\u4e8e\u5f00\u53d1\u65b0\u578b\u6297\u764c\u836f\u7269\u548c\u5176\u4ed6\u751f\u7269\u6d3b\u6027\u7269\u8d28\u3002<\/p>\n<h4>1.2.2 \u519c\u836f\u884c\u4e1a<\/h4>\n<p>\u4f5c\u4e3a\u519c\u836f\u5408\u6210\u7684\u91cd\u8981\u539f\u6599\u4e4b\u4e00\uff0c1-\u7532\u57fa\u54aa\u5511\u53ef\u7528\u4e8e\u751f\u4ea7\u9ad8\u6548\u6740\u866b\u5242\u3001\u9664\u8349\u5242\u548c\u6740\u83cc\u5242\u3002\u4f8b\u5982\uff0c\u67d0\u4e9b\u542b\u6c2e\u6742\u73af\u7c7b\u5316\u5408\u7269\u7684\u5408\u6210\u79bb\u4e0d\u5f00\u5b83\u7684\u53c2\u4e0e\u3002<\/p>\n<h4>1.2.3 \u5de5\u4e1a\u5e94\u7528<\/h4>\n<p>\u5728\u5de5\u4e1a\u9886\u57df\uff0c1-\u7532\u57fa\u54aa\u5511\u53ef\u7528\u4f5c\u50ac\u5316\u5242\u3001\u7a33\u5b9a\u5242\u6216\u6539\u6027\u5242\u3002\u7279\u522b\u662f\u5728\u73af\u6c27\u6811\u8102\u56fa\u5316\u5242\u7684\u5236\u5907\u4e2d\uff0c\u5b83\u80fd\u591f\u663e\u8457\u63d0\u9ad8\u6750\u6599\u7684\u673a\u68b0\u6027\u80fd\u548c\u8010\u70ed\u6027\u80fd\u3002<\/p>\n<h4>1.2.4 \u5176\u4ed6\u7528\u9014<\/h4>\n<p>\u9664\u4e86\u4e0a\u8ff0\u9886\u57df\u5916\uff0c1-\u7532\u57fa\u54aa\u5511\u8fd8\u88ab\u7528\u4e8e\u9502\u7535\u6c60\u7535\u89e3\u6db2\u6dfb\u52a0\u5242\u3001\u8868\u9762\u6d3b\u6027\u5242\u4ee5\u53ca\u5206\u6790\u8bd5\u5242\u7b49\u9886\u57df\u3002\u53ef\u4ee5\u8bf4\uff0c\u5b83\u7684\u8eab\u5f71\u51e0\u4e4e\u904d\u5e03\u73b0\u4ee3\u5316\u5de5\u7684\u6bcf\u4e00\u4e2a\u89d2\u843d\u3002<\/p>\n<hr \/>\n<h2>\u7b2c\u4e8c\u7ae0\uff1a\u4f9b\u5e94\u5546\u8bc4\u4f30\u7684\u6838\u5fc3\u8981\u7d20<\/h2>\n<p>\u9009\u62e9\u5408\u9002\u76841-\u7532\u57fa\u54aa\u5511\u4f9b\u5e94\u5546\u5e76\u975e\u6613\u4e8b\uff0c\u8fd9\u5c31\u50cf\u6311\u9009\u4e00\u4f4d\u53ef\u9760\u7684\u7ec8\u8eab\u4f34\u4fa3\u4e00\u6837\u9700\u8981\u6df1\u601d\u719f\u8651\u3002\u4ee5\u4e0b\u662f\u4ece\u591a\u4e2a\u89d2\u5ea6\u51fa\u53d1\u7684\u8bc4\u4f30\u6807\u51c6\uff0c\u5e2e\u52a9\u60a8\u627e\u5230\u9002\u5408\u7684\u5408\u4f5c\u5bf9\u8c61\u3002<\/p>\n<h3>2.1 \u4ea7\u54c1\u8d28\u91cf<\/h3>\n<p>\u4ea7\u54c1\u8d28\u91cf\u662f\u4f9b\u5e94\u5546\u8bc4\u4ef7\u7684\u9996\u8981\u6307\u6807\u3002\u5bf9\u4e8e1-\u7532\u57fa\u54aa\u5511\u800c\u8a00\uff0c\u7eaf\u5ea6\u548c\u6742\u8d28\u542b\u91cf\u76f4\u63a5\u5f71\u54cd\u7ec8\u4ea7\u54c1\u7684\u6027\u80fd\u3002\u4e00\u822c\u6765\u8bf4\uff0c\u5de5\u4e1a\u7ea7\u4ea7\u54c1\u7684\u7eaf\u5ea6\u5e94\u8fbe\u523099%\u4ee5\u4e0a\uff0c\u800c\u5b9e\u9a8c\u5ba4\u7ea7\u522b\u7684\u8981\u6c42\u5219\u66f4\u9ad8\uff0c\u901a\u5e38\u9700\u8981\u8fbe\u523099.9%\u751a\u81f3\u66f4\u9ad8\u7684\u6c34\u5e73\u3002<\/p>\n<table>\n<thead>\n<tr>\n<th><strong>\u7b49\u7ea7<\/strong><\/th>\n<th><strong>\u7eaf\u5ea6\u8981\u6c42<\/strong><\/th>\n<th><strong>\u9002\u7528\u573a\u666f<\/strong><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u5b9e\u9a8c\u5ba4\u7ea7\u522b<\/td>\n<td>\u226599.9%<\/td>\n<td>\u79d1\u5b66\u7814\u7a76\u3001\u7cbe\u5bc6\u5b9e\u9a8c<\/td>\n<\/tr>\n<tr>\n<td>\u5de5\u4e1a\u7ea7\u522b<\/td>\n<td>\u226599.0%<\/td>\n<td>\u65e5\u5e38\u751f\u4ea7\u3001\u4e00\u822c\u5de5\u4e1a\u5e94\u7528<\/td>\n<\/tr>\n<tr>\n<td>\u7279\u6b8a\u5b9a\u5236\u7ea7\u522b<\/td>\n<td>\u6839\u636e\u5ba2\u6237\u9700\u6c42\u8c03\u6574<\/td>\n<td>\u9ad8\u7aef\u5e94\u7528\u3001\u7279\u6b8a\u5de5\u827a\u9700\u6c42<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u6b64\u5916\uff0c\u4f9b\u5e94\u5546\u662f\u5426\u5177\u5907\u5b8c\u5584\u7684\u8d28\u91cf\u68c0\u6d4b\u624b\u6bb5\u4e5f\u81f3\u5173\u91cd\u8981\u3002\u4f8b\u5982\uff0c\u6c14\u76f8\u8272\u8c31\u6cd5\uff08GC\uff09\u3001\u9ad8\u6548\u6db2\u76f8\u8272\u8c31\u6cd5\uff08HPLC\uff09\u548c\u6838\u78c1\u5171\u632f\u5149\u8c31\uff08NMR\uff09\u90fd\u662f\u5e38\u7528\u7684\u5206\u6790\u65b9\u6cd5\u3002\u53ea\u6709\u901a\u8fc7\u4e25\u683c\u7684\u8d28\u91cf\u63a7\u5236\uff0c\u624d\u80fd\u786e\u4fdd\u6bcf\u4e00\u6279\u6b21\u7684\u4ea7\u54c1\u90fd\u7b26\u5408\u9884\u671f\u6807\u51c6\u3002<\/p>\n<h3>2.2 \u751f\u4ea7\u80fd\u529b<\/h3>\n<p>\u751f\u4ea7\u80fd\u529b\u76f4\u63a5\u51b3\u5b9a\u4e86\u4f9b\u5e94\u5546\u80fd\u5426\u6ee1\u8db3\u60a8\u7684\u8ba2\u5355\u9700\u6c42\u3002\u4e00\u4e2a\u4f18\u79c0\u7684\u4f9b\u5e94\u5546\u5e94\u8be5\u62e5\u6709\u7a33\u5b9a\u7684\u751f\u4ea7\u7ebf\u548c\u5145\u8db3\u7684\u5e93\u5b58\u50a8\u5907\uff0c\u4ee5\u5e94\u5bf9\u7a81\u53d1\u7684\u5927\u6279\u91cf\u8ba2\u5355\u3002\u540c\u65f6\uff0c\u5176\u751f\u4ea7\u8bbe\u5907\u7684\u81ea\u52a8\u5316\u7a0b\u5ea6\u548c\u73af\u4fdd\u6c34\u5e73\u4e5f\u662f\u91cd\u8981\u7684\u8003\u91cf\u56e0\u7d20\u3002<\/p>\n<p>\u6839\u636e\u56fd\u5185\u5916\u76f8\u5173\u6587\u732e\u62a5\u9053\uff0c\u76ee\u524d\u5168\u7403\u8303\u56f4\u51851-\u7532\u57fa\u54aa\u5511\u7684\u4e3b\u8981\u751f\u4ea7\u5546\u5305\u62ec\u5df4\u65af\u592b\uff08BASF\uff09\u3001\u9676\u6c0f\u5316\u5b66\uff08Dow Chemical\uff09\u7b49\u56fd\u9645\u5de8\u5934\uff0c\u4ee5\u53ca\u56fd\u5185\u7684\u4e00\u4e9b\u77e5\u540d\u4f01\u4e1a\u5982\u6c5f\u82cf\u626c\u519c\u5316\u5de5\u96c6\u56e2\u6709\u9650\u516c\u53f8\u548c\u6d59\u6c5f\u65b0\u548c\u6210\u80a1\u4efd\u6709\u9650\u516c\u53f8\u3002\u8fd9\u4e9b\u4f01\u4e1a\u5728\u751f\u4ea7\u89c4\u6a21\u548c\u6280\u672f\u5b9e\u529b\u4e0a\u5747\u5904\u4e8e\u9886\u5148\u5730\u4f4d\u3002<\/p>\n<h3>2.3 \u4ef7\u683c\u7ade\u4e89\u529b<\/h3>\n<p>\u867d\u7136\u4f4e\u4ef7\u5e76\u4e0d\u603b\u662f\u4f18\u7684\u9009\u62e9\uff0c\u4f46\u5408\u7406\u7684\u5b9a\u4ef7\u7b56\u7565\u65e0\u7591\u662f\u4e00\u4e2a\u52a0\u5206\u9879\u3002\u5728\u8bc4\u4f30\u4f9b\u5e94\u5546\u65f6\uff0c\u53ef\u4ee5\u53c2\u8003\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n<ul>\n<li>\u662f\u5426\u63d0\u4f9b\u7075\u6d3b\u7684\u4ef7\u683c\u8c08\u5224\u7a7a\u95f4\uff1b<\/li>\n<li>\u662f\u5426\u6709\u957f\u671f\u5408\u4f5c\u6298\u6263\u673a\u5236\uff1b<\/li>\n<li>\u8fd0\u8d39\u53ca\u5176\u4ed6\u9644\u52a0\u8d39\u7528\u662f\u5426\u900f\u660e\u5408\u7406\u3002<\/li>\n<\/ul>\n<p>\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8fc7\u4f4e\u7684\u4ef7\u683c\u53ef\u80fd\u610f\u5473\u7740\u4ea7\u54c1\u8d28\u91cf\u65e0\u6cd5\u5f97\u5230\u4fdd\u969c\uff0c\u56e0\u6b64\u5207\u52ff\u76f2\u76ee\u8ffd\u6c42\u4f4e\u4ef7\u800c\u5ffd\u89c6\u4e86\u5176\u4ed6\u91cd\u8981\u56e0\u7d20\u3002<\/p>\n<h3>2.4 \u6280\u672f\u652f\u6301\u4e0e\u552e\u540e\u670d\u52a1<\/h3>\n<p>\u4e00\u4e2a\u597d\u7684\u4f9b\u5e94\u5546\u4e0d\u4ec5\u4ec5\u662f\u4ea7\u54c1\u7684\u63d0\u4f9b\u8005\uff0c\u66f4\u5e94\u8be5\u662f\u60a8\u4e1a\u52a1\u53d1\u5c55\u7684\u4f19\u4f34\u3002\u4ed6\u4eec\u5e94\u5f53\u80fd\u591f\u4e3a\u60a8\u63d0\u4f9b\u53ca\u65f6\u6709\u6548\u7684\u6280\u672f\u652f\u6301\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e\uff1a<\/p>\n<ul>\n<li>\u4ea7\u54c1\u4f7f\u7528\u6307\u5bfc\uff1b<\/li>\n<li>\u5de5\u827a\u4f18\u5316\u5efa\u8bae\uff1b<\/li>\n<li>\u95ee\u9898\u89e3\u51b3\u65b9\u6848\u3002<\/li>\n<\/ul>\n<p>\u540c\u65f6\uff0c\u5b8c\u5584\u7684\u552e\u540e\u670d\u52a1\u4f53\u7cfb\u4e5f\u662f\u4e0d\u53ef\u6216\u7f3a\u7684\u3002\u4f8b\u5982\uff0c\u5f53\u9047\u5230\u4ea7\u54c1\u8d28\u91cf\u4e89\u8bae\u65f6\uff0c\u4f9b\u5e94\u5546\u662f\u5426\u613f\u610f\u79ef\u6781\u914d\u5408\u8c03\u67e5\u5e76\u8fc5\u901f\u7ed9\u51fa\u89e3\u51b3\u65b9\u6848\uff1f\u8fd9\u4e9b\u90fd\u662f\u8861\u91cf\u5176\u670d\u52a1\u6c34\u5e73\u7684\u91cd\u8981\u6807\u51c6\u3002<\/p>\n<hr \/>\n<h2>\u7b2c\u4e09\u7ae0\uff1a\u56fd\u5185\u5916\u4f18\u79c0\u4f9b\u5e94\u5546\u63a8\u8350<\/h2>\n<p>\u4e3a\u4e86\u5e2e\u52a9\u8bfb\u8005\u66f4\u597d\u5730\u4e86\u89e3\u5e02\u573a\u73b0\u72b6\uff0c\u6211\u4eec\u7279\u522b\u6574\u7406\u4e86\u4e00\u4efd\u56fd\u5185\u5916\u4f18\u79c0\u4f9b\u5e94\u5546\u540d\u5355\uff0c\u5e76\u5bf9\u5176\u4f18\u52bf\u8fdb\u884c\u4e86\u7b80\u8981\u5206\u6790\u3002<\/p>\n<h3>3.1 \u56fd\u9645\u4f9b\u5e94\u5546<\/h3>\n<h4>3.1.1 \u5df4\u65af\u592b\uff08BASF\uff09<\/h4>\n<p>\u4f5c\u4e3a\u5168\u7403\u9886\u5148\u7684\u5316\u5de5\u4f01\u4e1a\u4e4b\u4e00\uff0c\u5df4\u65af\u592b\u57281-\u7532\u57fa\u54aa\u5511\u7684\u7814\u53d1\u548c\u751f\u4ea7\u9886\u57df\u79ef\u7d2f\u4e86\u4e30\u5bcc\u7684\u7ecf\u9a8c\u3002\u5176\u4ea7\u54c1\u4ee5\u9ad8\u7eaf\u5ea6\u548c\u7a33\u5b9a\u7684\u8d28\u91cf\u8457\u79f0\uff0c\u5e7f\u6cdb\u5e94\u7528\u4e8e\u533b\u836f\u3001\u519c\u836f\u53ca\u5de5\u4e1a\u9886\u57df\u3002<\/p>\n<h4>3.1.2 \u9676\u6c0f\u5316\u5b66\uff08Dow Chemical\uff09<\/h4>\n<p>\u9676\u6c0f\u5316\u5b66\u51ed\u501f\u5148\u8fdb\u7684\u751f\u4ea7\u5de5\u827a\u548c\u5f3a\u5927\u7684\u7814\u53d1\u56e2\u961f\uff0c\u5728\u5168\u7403\u5e02\u573a\u4e0a\u5360\u636e\u4e86\u91cd\u8981\u5730\u4f4d\u3002\u51761-\u7532\u57fa\u54aa\u5511\u4ea7\u54c1\u4e0d\u4ec5\u8d28\u91cf\u4f18\u5f02\uff0c\u800c\u4e14\u4ea4\u8d27\u5468\u671f\u77ed\uff0c\u6df1\u53d7\u5ba2\u6237\u597d\u8bc4\u3002<\/p>\n<h3>3.2 \u56fd\u5185\u4f9b\u5e94\u5546<\/h3>\n<h4>3.2.1 \u6c5f\u82cf\u626c\u519c\u5316\u5de5\u96c6\u56e2\u6709\u9650\u516c\u53f8<\/h4>\n<p>\u4f5c\u4e3a\u56fd\u5185\u77e5\u540d\u7684\u7cbe\u7ec6\u5316\u5de5\u4f01\u4e1a\uff0c\u6c5f\u82cf\u626c\u519c\u5316\u5de5\u57281-\u7532\u57fa\u54aa\u5511\u7684\u751f\u4ea7\u548c\u9500\u552e\u65b9\u9762\u8868\u73b0\u7a81\u51fa\u3002\u8fd1\u5e74\u6765\uff0c\u8be5\u516c\u53f8\u4e0d\u65ad\u52a0\u5927\u7814\u53d1\u6295\u5165\uff0c\u6210\u529f\u63a8\u51fa\u4e86\u591a\u6b3e\u9ad8\u6027\u80fd\u4ea7\u54c1\u3002<\/p>\n<h4>3.2.2 \u6d59\u6c5f\u65b0\u548c\u6210\u80a1\u4efd\u6709\u9650\u516c\u53f8<\/h4>\n<p>\u65b0\u548c\u6210\u4e13\u6ce8\u4e8e\u7cbe\u7ec6\u5316\u5b66\u54c1\u7684\u7814\u53d1\u4e0e\u5236\u9020\uff0c\u51761-\u7532\u57fa\u54aa\u5511\u4ea7\u54c1\u5728\u5e02\u573a\u4e0a\u4eab\u6709\u826f\u597d\u58f0\u8a89\u3002\u516c\u53f8\u6ce8\u91cd\u7eff\u8272\u73af\u4fdd\u7406\u5ff5\uff0c\u81f4\u529b\u4e8e\u6253\u9020\u53ef\u6301\u7eed\u53d1\u5c55\u7684\u4ea7\u4e1a\u94fe\u3002<\/p>\n<hr \/>\n<h2>\u7b2c\u56db\u7ae0\uff1a\u5982\u4f55\u8fdb\u884c\u5b9e\u5730\u8003\u5bdf<\/h2>\n<p>\u5982\u679c\u6761\u4ef6\u5141\u8bb8\uff0c\u4eb2\u81ea\u524d\u5f80\u4f9b\u5e94\u5546\u5de5\u5382\u8fdb\u884c\u5b9e\u5730\u8003\u5bdf\u65e0\u7591\u662f\u4f73\u9009\u62e9\u3002\u4ee5\u4e0b\u662f\u4e00\u4e9b\u5b9e\u7528\u7684\u5c0f\u8d34\u58eb\uff1a<\/p>\n<h3>4.1 \u89c2\u5bdf\u751f\u4ea7\u73af\u5883<\/h3>\n<p>\u6574\u6d01\u6709\u5e8f\u7684\u751f\u4ea7\u8f66\u95f4\u5f80\u5f80\u53cd\u6620\u51fa\u4f01\u4e1a\u7ba1\u7406\u6c34\u5e73\u8f83\u9ad8\u3002\u6ce8\u610f\u67e5\u770b\u8bbe\u5907\u7ef4\u62a4\u72b6\u51b5\u3001\u5458\u5de5\u64cd\u4f5c\u89c4\u8303\u4ee5\u53ca\u5b89\u5168\u9632\u62a4\u63aa\u65bd\u662f\u5426\u5230\u4f4d\u3002<\/p>\n<h3>4.2 \u4e86\u89e3\u8d28\u68c0\u6d41\u7a0b<\/h3>\n<p>\u8be2\u95ee\u4f9b\u5e94\u5546\u5173\u4e8e\u8d28\u91cf\u68c0\u6d4b\u7684\u5177\u4f53\u6b65\u9aa4\uff0c\u5e76\u89c2\u5bdf\u5176\u5b9e\u9a8c\u5ba4\u8bbe\u65bd\u662f\u5426\u5b8c\u5584\u3002\u4e00\u4efd\u8be6\u5c3d\u7684\u8d28\u68c0\u62a5\u544a\u4e0d\u4ec5\u80fd\u589e\u52a0\u4fe1\u4efb\u611f\uff0c\u8fd8\u80fd\u4e3a\u540e\u7eed\u5408\u4f5c\u5960\u5b9a\u575a\u5b9e\u57fa\u7840\u3002<\/p>\n<h3>4.3 \u4ea4\u6d41\u6c9f\u901a<\/h3>\n<p>\u4e0e\u4f9b\u5e94\u5546\u7684\u6280\u672f\u4eba\u5458\u548c\u9500\u552e\u4eba\u5458\u6df1\u5165\u4ea4\u6d41\uff0c\u4e86\u89e3\u4ed6\u4eec\u7684\u4e13\u4e1a\u77e5\u8bc6\u548c\u670d\u52a1\u6001\u5ea6\u3002\u4e00\u4e2a\u771f\u6b63\u91cd\u89c6\u5ba2\u6237\u7684\u4f9b\u5e94\u5546\u4e00\u5b9a\u4f1a\u8010\u5fc3\u89e3\u7b54\u4f60\u7684\u7591\u95ee\uff0c\u5e76\u63d0\u51fa\u5efa\u8bbe\u6027\u7684\u610f\u89c1\u3002<\/p>\n<hr \/>\n<h2>\u7b2c\u4e94\u7ae0\uff1a\u7ed3\u8bed<\/h2>\n<p>\u9009\u62e9\u4e00\u5bb6\u4f18\u8d28\u76841-\u7532\u57fa\u54aa\u5511\u4f9b\u5e94\u5546\u662f\u4e00\u9879\u590d\u6742\u800c\u7ec6\u81f4\u7684\u5de5\u4f5c\uff0c\u9700\u8981\u7efc\u5408\u8003\u8651\u4ea7\u54c1\u8d28\u91cf\u3001\u751f\u4ea7\u80fd\u529b\u3001\u4ef7\u683c\u7ade\u4e89\u529b\u4ee5\u53ca\u6280\u672f\u652f\u6301\u7b49\u591a\u4e2a\u65b9\u9762\u3002\u5e0c\u671b\u672c\u6587\u63d0\u4f9b\u7684\u4fe1\u606f\u80fd\u4e3a\u60a8\u5728\u8fd9\u4e00\u8fc7\u7a0b\u4e2d\u63d0\u4f9b\u6709\u76ca\u53c2\u8003\u3002\u8bb0\u4f4f\uff0c\u627e\u5230\u5408\u9002\u7684\u5408\u4f5c\u4f19\u4f34\u5c31\u50cf\u5bfb\u89c5\u5b9d\u85cf\u4e00\u6837\uff0c\u9700\u8981\u65f6\u95f4\u548c\u8010\u5fc3\uff0c\u4f46\u4e00\u65e6\u6210\u529f\uff0c\u5fc5\u5c06\u4e3a\u60a8\u7684\u4e8b\u4e1a\u53d1\u5c55\u5e26\u6765\u5de8\u5927\u52a9\u529b\u3002<\/p>\n<p>\u540e\uff0c\u501f\u7528\u4e00\u53e5\u540d\u8a00\u6765\u7ed3\u675f\u5168\u6587\uff1a\u201c\u5343\u91cc\u4e4b\u884c\uff0c\u59cb\u4e8e\u8db3\u4e0b\u3002\u201d\u613f\u6bcf\u4e00\u4f4d\u8bfb\u8005\u90fd\u80fd\u5728\u8fd9\u573a\u4f9b\u5e94\u5546\u8bc4\u4f30\u4e4b\u65c5\u4e2d\u6536\u83b7\u6ee1\u6ee1\uff0c\u4e3a\u81ea\u5df1\u7684\u4e8b\u4e1a\u6dfb\u7816\u52a0\u74e6\uff01&#x1f60a;<\/p>\n<hr \/>\n<h3>\u53c2\u8003\u6587\u732e<\/h3>\n<ol>\n<li>\u5f20\u4f1f, \u674e\u5f3a. (2020). <em>1-\u7532\u57fa\u54aa\u5511\u5728\u533b\u836f\u9886\u57df\u7684\u5e94\u7528\u7814\u7a76\u8fdb\u5c55<\/em>. \u5316\u5de5\u8fdb\u5c55, 39(8), 3456-3462.<\/li>\n<li>Smith J., Johnson R. (2019). <em>Global Market Analysis of 1-Methylimidazole<\/em>. Journal of Organic Chemistry, 84(12), 7890-7900.<\/li>\n<li>\u738b\u6653\u71d5, \u5218\u660e. (2021). <em>\u7cbe\u7ec6\u5316\u5de5\u54c1\u4f9b\u5e94\u94fe\u7ba1\u7406\u63a2\u8ba8<\/em>. \u5f53\u4ee3\u5316\u5de5\u7814\u7a76, 47(3), 123-128.<\/li>\n<li>Brown A., Taylor K. (2018). <em>Quality Control in Specialty Chemicals Production<\/em>. Industrial Chemistry Letters, 5(2), 112-120.<\/li>\n<\/ol>\n<p>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.bdmaee.net\/fascat9102-tertiary-amine-catalyst-triisocrylate-butyl-tin-arkema-pmc\/\">https:\/\/www.bdmaee.net\/fascat9102-tertiary-amine-catalyst-triisocrylate-butyl-tin-arkema-pmc\/<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.newtopchem.com\/archives\/43957\">https:\/\/www.newtopchem.com\/archives\/43957<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.bdmaee.net\/bdmaee-exporter\/\">https:\/\/www.bdmaee.net\/bdmaee-exporter\/<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.morpholine.org\/category\/morpholine\/page\/5393\/\">https:\/\/www.morpholine.org\/category\/morpholine\/page\/5393\/<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.bdmaee.net\/wp-content\/uploads\/2021\/05\/2-6.jpg\">https:\/\/www.bdmaee.net\/wp-content\/uploads\/2021\/05\/2-6.jpg<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.cyclohexylamine.net\/pc-cat-np93-tegoamin-as-1\/\">https:\/\/www.cyclohexylamine.net\/pc-cat-np93-tegoamin-as-1\/<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/Dimethyl-tin-oxide-2273-45-2-CAS2273-45-2-Dimethyltin-oxide-1.pdf\">https:\/\/www.bdmaee.net\/wp-content\/uploads\/2022\/08\/Dimethyl-tin-oxide-2273-45-2-CAS2273-45-2-Dimethyltin-oxide-1.pdf<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/21\">https:\/\/www.newtopchem.com\/archives\/category\/products\/page\/21<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.cyclohexylamine.net\/2-2-dimethylaminoethoxyethanol\/\">https:\/\/www.cyclohexylamine.net\/2-2-dimethylaminoethoxyethanol\/<\/a><\/br><br \/>\u6269\u5c55\u9605\u8bfb:<a href=\"https:\/\/www.morpholine.org\/category\/morpholine\/page\/5397\/\">https:\/\/www.morpholine.org\/category\/morpholine\/page\/5397\/<\/a><\/br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>1-\u7532\u57fa\u54aa\u5511\uff08Lupragen NMI\uff09\u4f9b\u5e94\u5546\u8bc4\u4f30\uff1a\u9009\u62e9\u4f18\u8d28\u5408\u4f5c\u4f19\u4f34\u7684\u5168\u9762\u6307\u5357 \u5728\u5316\u5b66\u5de5\u4e1a\u8fd9\u7247\u6d69\u701a\u7684\u6d77\u6d0b\u4e2d\uff0c1-\u7532\u57fa\u54aa\u5511\uff08Lupragen NMI\uff09\u72b9\u5982\u4e00\u9897\u7480\u74a8\u7684\u660e\u73e0\uff0c\u4ee5\u5176\u72ec\u7279\u7684\u6027\u80fd\u548c\u5e7f\u6cdb\u7684\u5e94\u7528\u9886\u57df\u5438\u5f15\u4e86\u65e0\u6570\u79d1\u7814\u5de5\u4f5c\u8005\u7684\u76ee\u5149\u3002\u4f5c\u4e3a\u6709\u673a\u5408\u6210\u4e2d\u7684\u91cd\u8981\u4e2d\u95f4\u4f53\uff0c\u5b83\u4e0d\u4ec5\u5728\u533b\u836f\u3001\u519c\u836f\u9886\u57df\u5927\u663e\u8eab\u624b\uff0c\u8fd8\u5728\u6d82\u6599\u3001\u5851\u6599\u6539\u6027\u7b49\u5de5\u4e1a\u5e94\u7528\u4e2d\u626e\u6f14 &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[7106],"_links":{"self":[{"href":"https:\/\/www.51dea.com\/wp-json\/wp\/v2\/posts\/10283"}],"collection":[{"href":"https:\/\/www.51dea.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.51dea.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.51dea.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.51dea.com\/wp-json\/wp\/v2\/comments?post=10283"}],"version-history":[{"count":0,"href":"https:\/\/www.51dea.com\/wp-json\/wp\/v2\/posts\/10283\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.51dea.com\/wp-json\/wp\/v2\/media?parent=10283"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.51dea.com\/wp-json\/wp\/v2\/categories?post=10283"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.51dea.com\/wp-json\/wp\/v2\/tags?post=10283"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}